نوع مقاله : مقاله پژوهشی

نویسندگان

1 مربی/دانشگاه علوم پزشکی کرمانشاه

2 عضو هیات علمی

3 null

چکیده

مداخله روان‌شناختی جامع‌نگر برنامه درمانی نوینی است که بر اساس مشکلات و نیازهای روانی افراد نابارور طراحی شده است. هدف از پژوهش حاضر بررسی اثربخشی مداخله روان‌شناختی جامع‌نگر بر سلامت روان‌شناختی و نرخ بارداری زنان با ناباروری نامشخص و تحت درمان لقاح آزمایشگاهی است. بدین منظور با استفاده از نمونه‌گیری دردسترس از میان کلیه زنان نابارور مراجعه کننده به مرکز ناباروری معتضدی کرمانشاه 30 زن نابارور تحت درمان IVF که در دو حیطه از سه حیطه مقیاس21DASS- نمره متوسط به بالا داشتند، انتخاب و به شیوه تخصیص تصادفی در دو گروه قرار گرفتند. گروه آزمایشی تحت 11 جلسه مداخله روان‌شناختی جامع‌نگر 120 دقیقه‌ای قرار گرفت. گروه کنترل هیچ مداخله درمانی را دریافت نکرد. شرکت‌کنندگان قبل و بعد از مداخله و در پیگیری یک ماهه، مقیاس افسردگی، اضطراب و استرس 21DASS- را تکمیل کردند. نرخ بارداری در دو گروه بر اساس نتیجه آزمایش βHCG سنجیده شد. تحلیل داده‌ها با روش کوواریانس چند متغیره نشان داد که مداخله روان‌شناختی جامع‌نگر در مرحله پس آزمون به طور معنی‌داری موجب کاهش افسردگی، اضطراب و استرس گروه آزمایشی شده بود (001/0< p)، و این تأثیر در پیگیری یک ماهه همچنان تداوم داشت (001/0< p). نرخ بارداری در گروه آزمایشی 7/46% و در گروه کنترل 3/13% به دست آمد و از نظر آماری معنی‌دار بود (05/0>p). به عبارت دیگر مداخله روان‌شناختی جامع‌نگر در کاهش اضطراب، افسردگی و استرس و افزایش سلامت روان‌شناختی و نرخ بارداری زنان با نابارور نامشخص تحت درمان لقاح آزمایشگاهی مؤثر است.

کلیدواژه‌ها

عنوان مقاله [English]

The effectiveness of holistic-oriented psychological intervention on psychological health and pregnancy rate of unexplained infertile women undergoing IVF

نویسندگان [English]

  • monir hossinie 1
  • Iran Davoudi 2
  • null null 2
  • null null 3

1 psychologist

2 teacher

چکیده [English]

Intoduction
The desire of having a child is one of the most important functions of family and is also a base for human survival. Infertility is considered as a failure that is accompanied by physical and psychological tensions in family and society as well. Different psychological methods have been already utilized to help infertile people. The holistic-oriented psychological intervention (HPI) is a new therapeutic plan with bio-psycho-social pattern that has been designed according to psychological problems and needs of infertile people. After determining tension factors this therapeutic plan chooses techniques with high effectiveness rate in solving the mentioned problems, using eclectic techniques. The aim of present study is to examine the effectiveness of HPT on psychological health and fertility rate in women with unexplainable infertility undergoing in vitro fertilization treatment (IVF).
 
Method
The design of this study was a quasi- experimental one with pretest-posttest of experimental and control group. Thirty infertile women, undergoing IVF treatment, were selected, using available sampling. The sample was selected from among patients who referred to Moatazedi Infertility Center, Kermanshah, Iran. They completed two subscales of three subscales of DASS-21 scale who got the above average score. They were randomly assigned to two groups (each group 15 subjects). The experimental group was treated by the holistic-oriented psychological intervention for 11 sessions of 120-minutes. The control group did not receive any intervention. Participants completed the Depression, Anxiety and Stress Scale before and after intervention and after one month later. The pregnancy rate was measured in two groups based on the β-HCG test result. Data were analyzed by SPSS software (version 21).
 
Results
The results of multivariate covariance analysis  indicated that depression, anxiety and stress levels in the experimental group (p = 0.0001), significantly decreased in posttest group after holistic-oriented psychological intervention and this effect was observed and lasted in the one month follow up (p = 0.0001). The pregnancy rate in the experimental group was 46.7% and in the control group was 13.3% which were statistically significant (p <0.05).
 
Discussion
The results of this study showed that the holistic-oriented psychological intervention is effective in decreasing anxiety, depression and stress and increasing the psychological health and pregnancy rate of women with unexplainable infertility under In-Vitro Fertilization treatment.

کلیدواژه‌ها [English]

  • holistic-oriented psychological intervention
  • psychological health
  • unexplained Infertility
  • IVF
  • pregnancy rate
Andrews, F. M., Abbey, A., & Halman, L. J. (1992). Is fertility problem stress different? The dynamics of stress in fertile and infertile couples. Fertilility and Sterility, 57, 1247-53.
Behjatie-Ardekanie, Z., Akhondie, M.M., Kamalie, K., fazli-khalf, Z., Eskandari, S.H., & Ghorbani, B. (2011). Evaluation of mental health of the infertility woman referred to Ebne-Sina Reproduvtive clinic. Journal of Reproduction & Infertility, 11 (4), 319-324. [Persian].
Berek , J. S. (2012). Berek and Novak's Gynecology. 15th Ed. Lippincott Williams and Wilkins,
Boivin, J., & Gameiro, S.(2015). Evolution of psychology and counseling in infertility. Fertility and Sterility, 104 (2), 115-123.
De Klerk, C., Heijnen, E. M., Macklon, N. S., Duivenvoorden, H. J., Fauser, B. C., & Passchier, J. (2006). The psychological impact of mild ovarian stimulation combined with single embryo transfer compared with conventional IVF. Human Reproduction, 21 (3), 721-727.
Diamond, R. K., Meyers, M., Scharf, C. N., & Weinshel, M. (1999). Couple Therapy for Infertility. 1th ed, New York: The Guilford Press.
Domar, A. D., & Lauren, B. (2011). Impact of psychological interventions on IVF outcome. Srm, 9 (427), 26-32.
Frederiksen, Y., Farver-Vestergaard, I., Skovgard, N. G., Ingerslev, H. G., & Zachariae, R. (2015). Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis. BMJ Open, 5 (1), http://bmjopen.bmj.com.
Gibbs, R. S., Karlan, B. Y., Haney, A. F., & Nygaard, I. E. (2008). Danforth's Obstetrics and Gynecology. 10th Ed, Lippincott Williams & Wilkins.
Haemmerli, K., Znoj, H., & Barth, J. (2009). The efficacy of psychological interventions for infertile patients: A meta-analysis examining mental health and pregnancy rate. Humam Reproduction Update, 15 (3), 279-295.
Heidari, P., & Latifnejad Roudsari, R. (2010 ). Relationship between psychosocial factors and marital satisfaction in infertile women. Journal of Qazvin University of Medical, 1 (54), 26-32.[Persian] 
Hynes, G. J., Callan, V.J., Terry, D. J., & Allois, C. H. (1992). The psychological well-being of infertility women after a failed IVF attempt. British Journal of Medical psychology, 65, 269-278.
Janati, Y., & Khaki, N. (2013). Psychatric in midwife. 3ed. Tehran, Jamenegar. [Persian].
Kim, M., Kim, S., Chang, S., Yoo, J., Kyung Kim, H., & Cho, J.(2014). Effect of a Mind-Body Therapeutic Program for Infertile Women Repeating In Vitro Fertilization Treatment on Uncertainty, Anxiety, and Implantation Rate. Asian Nursing Research, 8, 49-56.
Khojastemeher, R., Movahedi, M., & Ragabi, G. R. (2010). The impact of training intimacy on couples communicative intimacy. Journal of Psychology Achievements, 4 (1), 53-68. [Persian].
Koszycki, D., Bisserbe, J. C., Blier, P., Bradwejn, J., & Markowitz, M.(2012). Interpersonal psychotherapy  versus brief supportive therapy for depressed infertile women: First pilot randomized controlled trial. Archives of Women's Mental Health. 15(3), 193-201.
Lovibond, P. F., & Lovibond, S. H. (1995). The structure of negative emotional states: Comparison of the depression anxiety inventories. Behavior Research and therapy, 33, 335-342.
Matthiesen, S., Klonoff-Cohen, H., Zachariae, R., Jensen-Johansen, M. B., Nielsen, B. K., Frederiksen, Y., Schmidt, L., & Ingerslev, H. J. (2012). The effect of an expressive writing intervention (EWI) on stress in infertile couples undergoing assisted reproductive technology (ART). British J of Health Psychology, 17, 362-378.
Olivius, C., Friden, B., Borg, G., & Bergh, C. (2004). Why do couples discontinue in-vitro fertilization treatment? A cohort study. Fertility and Sterility, 81 (2), 258-261.
Pal, L., Bevilacqua, K., & Santoro, N. F. (2010). Chronic psychosocial are detrimental to ovarian reserve: A study of infertile women. Journal of Psychosomatic Obstetrics & Gynecology. 31 (3), 130-139.
Peterson, B. D., Pirritano, M., Christensen, U., & Schmidt, L. (2008). The impact of partner coping in couples experiencing infertility. Human Reproduction, 23(5), 1128-37.
Pirkalani, K. K., & Talaee Rad, Z. (2013). Psychological stress causes relative infertility through direct change in the frequency pattern of gnrh release from the hypothalamus. European Psychiatry, 28(1), 1-8.
Ramazanzadeh, F., Noorbala, A. A., Abedinia N., & Naghiza-deh, M. M. (2011). Psychiatric intervention improved pregnancy rates in infertile couples. Malaysian Journal of Medical Sciences,18 (1), 16-24.
Ryan, K. J., Berkowitz, R. S., Barbieri, R. L., & Dunaif, A. (2006). Kistner’s Gynecology and Women’s Health. [B. Ghazi Jahani, B., Ghotb , R. trans].7th ed. Missouri: Mosby.
Sahebi, A., Asghari, M. J., Salari, R. (2005). Validation of Depression, Anxiety and Stress (DASS-21) for Iranian population. Iran Psychologists, 1, 50–60. [Persian].
Samani, S., & Jokar, B. (2007). Studying reliability and validity of the short-form version of the Depression Anxiety Stress Scale. journal of social sciences and humanities of shiraz university, 26 (3), 65-77. [Persian].
Simbar, M., Hashemi, S., Shams, G., & Alavi Majd, H. (2010). Relation of anxiety and outcome of ART in the infertility woman referred to selective clinic in Tehran. Journal Reproduction & Infertility, 10 (4), 279-285.

Smeenk, J. M., Verhaak, C. M., Eugster, A., Van Minnen, A., Zielhuis, G. A., & Braat, D. D. (2001). The effect of anxiety and depression on the outcome of in-vitro fertilization. Human Reproduction, 16 (7), 1420-1423.

Vahid Roudsari, F., Ayati, A., Mirzaeeyan, S., Shakeri, M. T., & Akhtardel, H. (2009). Fertility outcome after IVF and related factors. J Gorgan Univ Med Sci, 11 (3), 42-46. [Persian]
Ying, L., Wu, L. H., & Loke, A. Y. (2016). The effects of psychosocial interventions on the mental health, pregnancy rates, and marital function of infertile couples undergoing in vitro fertilization: a systematic review. Journal of Assisted Reproduction and Genetics, 16 (3), 211-219